

Indeed male sexual arousal has been conceived as a multidimensional experience involving cognitive, emotional and physiological components that relay on a widespread set of brain regions. These studies have permitted to disentangle the role played by several brain regions in different stages of visually driven sexual arousal. In the last decade, numerous functional neuroimaging studies have focused on the brain regions that are evoked by sexually relevant stimuli, showing an involvement of different cortical and subcortical structures, such as cingulate cortex, insula caudate nucleus, putamen, thalamus, amygdala and hypothalamus –. Epidemiological studies have shown a high prevalence and incidence of psychogenic ED among men.

Moreover, psychogenic ED represents a disorder related to psychosocial health and has a significant impact on the quality of life of both sufferers and their partners. Psychogenic Erectile Dysfunction (ED) has been defined as the persistent inability to attain and maintain an erection sufficient to permit sexual performance. Our findings help to elucidate a neural basis of psychogenic erectile dysfunction. We believe that this change can influence the motivation-related component of sexual behavior. Our results suggest that atrophy of nucleus accumbens plays an important role in psychogenic erectile dysfunction. In addition, a GM atrophy of left hypothalamus was also observed. Left nucleus accumbens volumes in patients correlated with low erectile functioning as measured by IIEF-5 (International Index of Erectile Function). Shape analysis showed that this atrophy was located in the left medial-anterior and posterior portion of accumbens. Significant GM atrophy of nucleus accumbens was observed bilaterally in patients with respect to controls. After Rigiscan evaluation, urological, general medical, metabolic and hormonal, psychological and psychiatric assessment, 17 outpatients with psychogenic ED and 25 healthy controls were recruited for structural MRI session. In this study, we determined the presence of grey matter (GM) atrophy patterns in subcortical structures such as amygdala, hippocampus, nucleus accumbens, caudate nucleus, putamen, pallidum, thalamus, and hypothalamus in patients with psychogenic ED and healthy men. In spite of the well-known involvement of subcortical regions such as hypothalamus and caudate nucleus in male sexual response, and the key role of nucleus accumbens in pleasure and reward, poor attention was paid to their role in male sexual dysfunction. Few neuroimaging studies have investigated the cerebral basis of erectile dysfunctions observing the role played by prefrontal, cingulate, and parietal cortices during erotic stimulation. It shows a high incidence and prevalence among men, with a significant impact on the quality of life. Here is what is in the button: if CImGui.Psychogenic erectile dysfunction (ED) has been defined as the persistent inability to attain and maintain an erection sufficient to permit sexual performance.

After clicking Generate plot, I want to generate new image(without the old one).
